(19)
(11) EP 1 742 911 A1

(12)

(43) Date of publication:
17.01.2007 Bulletin 2007/03

(21) Application number: 05738031.3

(22) Date of filing: 22.04.2005
(51) International Patent Classification (IPC): 
C07D 207/44(2006.01)
C07F 9/09(2006.01)
C07D 401/12(2006.01)
A61K 31/661(2006.01)
C07F 9/12(2006.01)
C07D 401/04(2006.01)
A61K 31/4015(2006.01)
A61P 35/00(2006.01)
(86) International application number:
PCT/GB2005/001553
(87) International publication number:
WO 2005/102997 (03.11.2005 Gazette 2005/44)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR

(30) Priority: 26.04.2004 EP 04291074

(71) Applicant: AstraZeneca AB
S-151 85 Södertälje (SE)

(72) Inventors:
  • ARNOULD, Jean-Claude, AstraZeneca Pharma
    51689 Reims Cedex 2 (FR)
  • HARRIS, Craig Steven, AstraZeneca Pharma
    51689 Reims Cedex 2 (FR)
  • BOYLE, Francis Thomas, AstraZeneca R & D Alderely
    Macclesfield, Cheshire SK10 4TG (GB)
  • GIBSON, Keith Hopkinson AstraZeneca R & D Alderley
    Macclesfield, Cheshire SK10 4TG (GB)

   


(54) 3,4-DISUBSTITUTED MALEIMIDES FOR USE AS VASCULAR DAMAGING AGENTS