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(11)

EP 1 742 959 A2

(12)

(88) Date of publication A3: 24.08.2006 (43) Date of publication: 17.01.2007 Bulletin 2007/03 (21) Application number: 05779587.4 (22) Date of filing: 26.04.2005

(51) International Patent Classification (IPC):  C07H 21/04(2006.01) (86) International application number: PCT/US2005/014361 (87) International publication number: WO 2005/113813 (01.12.2005 Gazette 2005/48)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR LV MK YU (30) Priority: 26.04.2004 US 565601 P 24.05.2004 US 574120 P 22.06.2004 US 581865 P 07.03.2005 US 660204 P (71) Applicant: Archemix Corporation Cambridge, MA 02139 (US)

(72) Inventors: CLOAD, Sharon Cambridge, MA 02138 (US) DIENER, John L. Cambridge, MA 02139 (US) KEENE, Sara, Chesworth Tewksbury, MA 01876 (US) KURZ, Markus Newton, MA 02465 (US) LAGASSE, H., A., Daniel Somerville, MA 02143 (US) MARSH, Harold, Nicholas Charlestown, MA 02129 (US) SAWHNEY, Pooja Arlington, MA 02474 (US) WANG, Chunhua Acton, MA 01720 (US) (74) Representative: Clegg, Richard Ian et al Mewburn Ellis LLP York House 23 Kingsway London WC2B 6HP London WC2B 6HP (GB)