(19)
(11) EP 1 743 635 A3

(12) EUROPEAN PATENT APPLICATION

(88) Date of publication A3:
24.10.2007 Bulletin 2007/43

(43) Date of publication A2:
17.01.2007 Bulletin 2007/03

(21) Application number: 06020883.2

(22) Date of filing: 05.01.1996
(51) International Patent Classification (IPC): 
A61K 31/365(2006.01)
A61K 31/215(2006.01)
A61P 17/02(2006.01)
 A61K 31/19(2006.01)
A61K 45/06(2006.01)
(84) Designated Contracting States:
AT BE CH DE ES FR GB IE IT LI NL PT SE

(30) Priority: 06.01.1995 AU PN042095
24.11.1995 AU PN677795
05.12.1995 AU PN697795

(62) Application number of the earlier application in accordance with Art. 76 EPC:
96900200.5 / 0800388

(71) Applicant: AUSTRALIAN BIOMEDICAL COMPANY PTY. LTD.
East Melbourne, VIC 3002 (AU)

(72) Inventors:
  • Wu, Minne
    Mount Waverley, Victoria, 3149 (AU)
  • Wu, David Shine
    Mount Waverley, Victoria, 3149 (AU)

(74) Representative: Gardner, Rebecca Katherine 
Frank B. Dehn & Co. St Bride's House 10 Salisbury Square
London EC4Y 8JD
London EC4Y 8JD (GB)

   


(54) Gibberellins for the promotion of ulcer healing


(57) Compounds of formula (1) (Gibberellins), and their pharmaceutically acceptable derivatives when used as promoters of ulcer-healing on animals, including humans, wherein A is COOR, where R is hydrogen, unsubstituted or substituted C1-20 alkyl, allyl, aryl, arylalkyl, amidine, NR4R5 or an unsaturated or saturated ring containing one or more heteroatoms. R4 and R5 may or may not be the same, are hydrogen, or C1-20 alkyl, allyl, aryl, aralkyl or an unsaturated or saturated ring containing one or more hetero-atoms; B is hydrogen, hydroxyl, mercaptan, halogen; or A and B together form a -CO-O- linkage; R1 is hydrogen, hydroxyl, mercaptan, halogen, amino, azido, NR4R5, unsubstituted or substituted C1-20 alkyl, allyl, aryl, arylalkyl; and R2 is methylene, hetero-atoms.









Search report