(19)

(11)

EP 1 744 787 A1

(12)

(43) Date of publication: 24.01.2007 Bulletin 2007/04 (21) Application number: 05746912.4 (22) Date of filing: 13.05.2005

(51) International Patent Classification (IPC):  A61K 47/48(2006.01) A61L 27/14(2006.01) A61K 47/30(2006.01) A61L 27/54(2006.01) (86) International application number: PCT/CA2005/000742 (87) International publication number: WO 2005/110485 (24.11.2005 Gazette 2005/47)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (30) Priority: 14.05.2004 CA 2467321 25.06.2004 US 875550 (71) Applicant: Interface Biologics Inc. Toronto, ON M5S 3H6 (CA)	(72) Inventors: SANTERRE, Paul, J., University of Toronto Toronto, Ontario M5G 1G8 (CA) LARONDE, Frank, J. Toronto, Ontario M5S 3H6 (CA) LI, Mei Toronto, Ontario M5S 3H6 (CA) (74) Representative: Roques, Sarah Elizabeth et al J.A. Kemp & Co. 14 South Square Gray's Inn London WC1R 5JJ London WC1R 5JJ (GB)