ATBECHDEDKESFRGBGRITLILUNLSEMCPTIESILTLVFIROMKCYALTRBGCZEEHUPLSKBAHRISYU........*JDIM360 Ver 2.15 (14 Jul 2008) - 2999001/01747201FASCICULE DE BREVET EUROPEEN CORRIGEB8B120090218W184deBibliographieenBibliographyfrBibliographieEP05770962.8200505102006121120070314frfrfr040505520040511FR2009021820090820070131200705200810152008422008011620090218200908C07D 231/54 20060101AFI20060105BHEP de2H- ODER 3H-BENZO[E]INDAZOL-1-YL-KARBAMAT-DERIVATE, HERSTELLUNG UND THERAPEUTISCHE VERWENDUNGen2H OR 3H-BENZO[E]INDAZOL-1-YLE CARBAMATE DERIVATIVES, THE PREPARATION AND THERAPEUTIC USE THEREOFfrDERIVES DE CARBAMATE DE 2H- OU 3H-BENZO[E]INDAZOL-1-YLE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUEEP-A- 0 607 076EP-A- 1 036 794WO-A-99/58117FR-A- 2 741 073YOKOYAMA, NAOKATA ET AL: "2-Arylpyrazolo[4,3-c]quinolin-3-ones: a novel agonist, a partial agonist and an antagonist of benzodiazepines" JOURNAL OF MEDICINAL CHEMISTRY, vol. 25, no. 4, 1982, pages 337-339, XP002312656LLOYD G K ET AL: "THE ACTIVITY OF ZOLPIDEM AND OTHER HYPNOTICS WITHIN THE GAMMA-AMINOBUTYRIC ACID (GABAA) RECEPTOR SUPRAMOLECULAR COMPLEX, AS DETERMINED BY 35S-T-BUTYLBICYCLOPHOPHOROTHIONATE (35S-TBPS) BINDING TO RAT CEREBRAL CORTEX MEMBRANES" JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, AMERICAN SOCIETY FOR PHARMACOLOGY AND, US, vol. 255, no. 2, octobre 1990 (1990-10), pages 690-696, XP008001863 ISSN: 0022-3565 & WEISSMAN, BEN A. ET AL: "Presence of peripheral benzodiazepine binding sites on primary rat skeletal fibroblasts" EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 187, no. 3, 1990, pages 369-375, XP002312657NAKAO, TOHRU ET AL: "Synthesis and biological activities of optical isomers of 2-(4-chlorophenyl)-5,6-dihydro-(1)benzothi epino[5,4-c]pyridazin- 3(2H)-one 7-oxide" CHEMICAL & PHARMACEUTICAL BULLETIN ( 1992 ), 40 (1), 117 -21 CODEN: CPBTAL; ISSN: 0009-2363, vol. 40, no. 1, 1992, pages 117-121, XP002312658PIPERAKI S ET AL: "Enantiomeric separation of zopiclone, its metabolites and products of degradation on a beta-cyclodextrin bonded phase" JOURNAL OF CHROMATOGRAPHY A, ELSEVIER SCIENCE, NL, vol. 729, no. 1, 5 avril 1996 (1996-04-05), pages 19-28, XP004039158 ISSN: 0021-9673OLIVIER A ET AL: "A conformational study of ligands for omega modulatory sites of GABAA receptors by noesy NMR spectroscopy and distance geometry" BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, OXFORD, GB, vol. 7, no. 17, 9 septembre 1997 (1997-09-09), pages 2277-2282, XP004136428 ISSN: 0960-894XRAO, V. L. RAGHAVENDRA ET AL: "Characterization of binding sites for the .omega.3 receptor ligands [3H]PK11195 and [3H]RO5-4864 in human brain" EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 340, no. 1, 1997, pages 89-99, XP002312659DUBOIS, Laurent132, avenue de la RésistanceF-92350 Le Plessis-RobinsonFREVANNO, Yannick12 rue de Courances91490 DannemoisFRMALOIZEL, Christian21, rue du PlateauF-92190 MeudonFRSEVRIN, Mireille3, rue Francis de PressenséF-75014 ParisFRSanofi-Aventis02783857SSL0231/AG174, Avenue de France75013 ParisFRMorel-Pécheux, Murielet al09234011sanofi-aventis Département Brevets 174 avenue de France75013 ParisFRATBEBGCHCYCZDEDKEEESFIFRGBGRHUIEISITLILTLUMCNLPLPTROSESISKTRAL20061211BA20061211HR20061211LV20061211MK20061211YU20061211FR200500115420050510frWO20051210992005122220055120070131200705