SUBSTANTIALLY PURE 2-{¬2-(2-METHYLAMINO-PYRIMIDIN-4-YL)-1H-INDOLE-5-CARBONYL|-AMINO}-3-(PHENYLPYRIDIN-2-YL-AMINO)-PROPIONIC ACID AS AN IKB KINASE INHIBITOR - Patent 1747215

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EP 1 747 215 A1

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(43)	Date of publication:
	31.01.2007 Bulletin 2007/05

(21)	Application number: 05749733.1

(22)	Date of filing: 11.05.2005

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International Patent Classification (IPC):

C07D 401/14^(2006.01)
A61P 11/06^(2006.01)

A61K 31/506^(2006.01)

(86)	International application number:
	PCT/US2005/016381

(87)	International publication number:
	WO 2005/113544 (01.12.2005 Gazette 2005/48)

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
	Designated Extension States:
	AL BA HR LV MK YU

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Priority:

12.05.2004 US 570146 P

(71)	Applicant: Aventis Pharmaceuticals Inc.
	Bridgewater, New Jersey 08807-0800 (US)

(72)	Inventors:
	HADDAD, El-Bdaoui Basking Ridge, NJ 07920 (US) RITZELER, Olaf D-65812 Bad Soden (DE) ALDOUS, David, J. Gillette, NJ 07933 (US) COX, Paul, Joseph Flemington, NJ 08822 (US)

(74)	Representative: Ori, Janos et al
	Chinoin Gyogyszer és Vegyészeti Termékek Gyara Rt. To u. 1-5. H-1045 Budapest H-1045 Budapest (HU)

(54)	SUBSTANTIALLY PURE 2-{¬2-(2-METHYLAMINO-PYRIMIDIN-4-YL)-1H-INDOLE-5-CARBONYL\|-AMINO}-3-(PHENYLPYRIDIN-2-YL-AMINO)-PROPIONIC ACID AS AN IKB KINASE INHIBITOR