(19)

(11)

EP 1 747 468 A2

(12)

(88) Date of publication A3: 02.03.2006 (43) Date of publication: 31.01.2007 Bulletin 2007/05 (21) Application number: 05738697.1 (22) Date of filing: 06.05.2005

(51) International Patent Classification (IPC):  G01N 33/68(2006.01) (86) International application number: PCT/IB2005/001234 (87) International publication number: WO 2005/109004 (17.11.2005 Gazette 2005/46)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (30) Priority: 06.05.2004 GB 0410101 (71) Applicant: K.U. Leuven Research and Development 3000 Leuven (BE)	(72) Inventors: BAEKELANDT, Veerle B-3001 Heverlee (BE) DEBYSER, Zeger B-3001 Heverlee (BE) ENGELBORGHS, Yves B-3001 Heverlee (BE) GERARD, Melanie B-8400 Oostende (BE) (74) Representative: Bird, Ariane et al Bird Goën & Co Klein Dalenstraat 42A 3020 Winksele 3020 Winksele (BE)