Infectious and attenuated bovine viral diarrhea virus vaccine

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EP 1 749 885 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	16.01.2013 Bulletin 2013/03

(45)	Mention of the grant of the patent:
	05.12.2012 Bulletin 2012/49

(21)	Application number: 06011790.0

(22)	Date of filing: 05.09.2002

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International Patent Classification (IPC):

C12N 7/04^(2006.01)
C07K 14/18^(2006.01)

A61K 39/12^(2006.01)

(54)	Infectious and attenuated bovine viral diarrhea virus vaccine Impfstoff von infektiösen und attenuierten Rinderdiarrhoeviren Vaccin infectieux et attenues du virus de la diarrhée virale bovine

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR

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Priority:

06.09.2001 DE 10143813

(43)	Date of publication of application:
	07.02.2007 Bulletin 2007/06

(62)	Application number of the earlier application in accordance with Art. 76 EPC:
	02797952.5 / 1440149

(73)	Proprietor: Boehringer Ingelheim Vetmedica GmbH
	55216 Ingelheim am Rhein (DE)

(72)	Inventors:
	Elbers, Knut 55216 Ingelheim am Rhein (DE) Fetzer, Christiane 48163 Münster (DE) von Freyburg, Martina 55131 Mainz (DE) Meyers, Gregor 17498 Neuenkirchen-Wampen (DE)

(74)	Representative: HOFFMANN EITLE
	Patent- und Rechtsanwälte Arabellastrasse 4 81925 München 81925 München (DE)

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References cited: :

WO-A-01/39801

MEYER CHRISTIANE ET AL: "Recovery of virulent and RNase-negative attenuated type 2 bovine viral diarrhea viruses from infectious cDNA clones." JOURNAL OF VIROLOGY, vol. 76, no. 16, August 2002 (2002-08), pages 8494-8503, XP002251604 August, 2002 ISSN: 0022-538X
DATABASE EMBL [Online] XP002251610 retrieved from EMBL Database accession no. AF145967 -& DATABASE EMBL [Online] 14 June 1999 (1999-06-14), XP002437779 retrieved from EMBL-SVA Database accession no. AF145967
RIDPATH JULIA F ET AL: "The genomic sequence of a virulent bovine viral diarrhea virus (BVDV) from the type 2 genotype: Detection of a large genomic insertion in a noncytopathic BVDV." VIROLOGY, vol. 212, no. 1, 1995, pages 39-46, XP002251605 ISSN: 0042-6822
ODEÓN A C ET AL: "Experimental infection of calves with bovine viral diarrhea virus genotype II (NY-93)." JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION: OFFICIAL PUBLICATION OF THE AMERICAN ASSOCIATION OF VETERINARY LABORATORY DIAGNOSTICIANS, INC. UNITED STATES MAY 1999, vol. 11, no. 3, May 1999 (1999-05), pages 221-228, XP009015305 ISSN: 1040-6387
TOPLIFF CHRISTINA L ET AL: "Virulence markers in the 5' untranslated region of genotype 2 bovine viral diarrhea virus isolates." VIROLOGY, vol. 250, no. 1, 10 October 1998 (1998-10-10), pages 164-172, XP002251606 ISSN: 0042-6822
KUEMMERER BEATE M ET AL: "Correlation between point mutations in NS2 and the viability and cytopathogenicity of Bovine viral diarrhea virus strain Oregon analyzed with an infectious cDNA clone." JOURNAL OF VIROLOGY, vol. 74, no. 1, January 2000 (2000-01), pages 390-400, XP002251607 ISSN: 0022-538X
MEYERS GREGOR ET AL: "Recovery of cytopathogenic and noncytopathogenic bovine viral diarrhea viruses from cDNA constructs." JOURNAL OF VIROLOGY, vol. 70, no. 12, 1996, pages 8606-8613, XP002251609 ISSN: 0022-538X
VASSILEV V ET AL: "Authentic and full-length genomic cDNA clones of BVDV that yield infectious transcripts" JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 71, no. 1, 1997, pages 471-478, XP002144456 ISSN: 0022-538X
VAN DER POEL W H ET AL: "Experimental reproduction of respiratory disease in calves with non-cell-culture-passaged bovine respiratory syncytial virus." THE VETERINARY QUARTERLY SEP 1996, vol. 18, no. 3, September 1996 (1996-09), pages 81-86, XP009041333 ISSN: 0165-2176

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).