(19)
(11) EP 1 750 775 A2

(12)

(43) Date of publication:
14.02.2007 Bulletin 2007/07

(21) Application number: 05804803.4

(22) Date of filing: 04.05.2005
(51) International Patent Classification (IPC): 
A61K 48/00(2006.01)
(86) International application number:
PCT/US2005/015574
(87) International publication number:
WO 2005/117991 (15.12.2005 Gazette 2005/50)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
Designated Extension States:
AL BA HR LV MK YU

(30) Priority: 04.05.2004 US 568027 P
12.05.2004 US 570512 P
12.05.2004 US 570513 P
27.09.2004 US 613416 P
25.02.2005 US 656572 P
01.04.2005 US 667833 P

(71) Applicant: Nastech Pharmaceutical Company Inc.
Bothell, WA 98021-8906 (US)

(72) Inventors:
  • CHEN, Lishan
    Bellevue, WA 98006 (US)
  • CUI, Kunyuan
    Bothell, WA 98012 (US)
  • CHEN, Yuching
    Bellevue, WA 98006 (US)
  • MAYER, Sasha, J.
    Snohomish, WA 98296 (US)

(74) Representative: MacLean, Martin Robert et al
Mathys & Squire 120 Holborn
London EC1N 2SQ
London EC1N 2SQ (GB)

   


(54) COMPOSITIONS AND METHODS FOR ENHANCING DELIVERY OF NUCLEIC ACIDS INTO CELLS AND FOR MODIFYING EXPRESSION OF TARGET GENES IN CELLS