(19)

(11)

EP 1 755 684 A2

(12)

(88) Date of publication A3: 03.08.2006 (43) Date of publication: 28.02.2007 Bulletin 2007/09 (21) Application number: 05746563.5 (22) Date of filing: 25.05.2005

(51) International Patent Classification (IPC):  A61K 47/48(2006.01) (86) International application number: PCT/GB2005/002084 (87) International publication number: WO 2005/117984 (15.12.2005 Gazette 2005/50)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR LV MK YU (30) Priority: 01.06.2004 GB 0412181 (71) Applicant: Celltech R&D Limited Slough, Berkshire SL1 3WE (GB)	(72) Inventors: EATON, Michael Anthony William Slough Berkshire SL1 3WE (GB) NORMAN, Timothy John Slough Berkshire SL1 3WE (GB) PORTER, John Robert Slough Berkshire SL1 3WE (GB) (74) Representative: Thompson, John et al UCB Celltech, 208 Bath Road Slough, Berkshire SL1 3WE Slough, Berkshire SL1 3WE (GB)