(19)
(11) EP 1 758 594 A1

(12)

(43) Date of publication:
07.03.2007 Bulletin 2007/10

(21) Application number: 04776045.9

(22) Date of filing: 19.05.2004
(51) International Patent Classification (IPC): 
A61K 31/663(2006.01)
A61P 19/02(2006.01)
A61P 19/10(2006.01)
 A61K 31/69(2006.01)
A61P 19/08(2006.01)
G01N 33/82(2006.01)
(86) International application number:
PCT/US2004/015743
(87) International publication number:
WO 2005/117906 (15.12.2005 Gazette 2005/50)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
Designated Extension States:
LV

(71) Applicant: Merck and Co., Inc.
Rahway, NJ 07065 (US)

(72) Inventors:
  • DAIFOTIS, Anastasia, G.
    Rahway, NJ 07065 (US)
  • DENKER, Andrew
    Rahway, NJ 07065 (US)
  • IKEDA, Craig
    Rahway, NJ 07065 (US)
  • MATUSZEWSKI, Bogdan, K.
    Rahway, NJ 07065 (US)
  • MAZEL, Sid
    Rahway, NJ 07065 (US)
  • PORRAS, Arturo, G.
    Rahway, NJ 07065 (US)
  • SANTORA, Art
    Rahway, NJ 07065 (US)
  • SEBURG, Randal, Alan
    Rahway, NJ 07065 (US)
  • ZHU, Limin
    Rahway, NJ 07065 (US)
  • YATES, John
    Rahway, NJ 07065 (US)
  • KIRSCH, John, D.
    Rahway, NJ 07065 (US)

(74) Representative: Harris, Jennifer Lucy et al
Kilburn & Strode 20 Red Lion Street
GB-London WC1R 4PJ
GB-London WC1R 4PJ (GB)

   


(54) COMBINATION FOR INHIBITING BONE RESORPTION COMPRISING A BISPHOSPONATE (ALENDRONA) AND A VITAMIN D (CHOLECALCIFEROL)