(19)
(11) EP 1 758 640 A2

(12)

(43) Date of publication:
07.03.2007 Bulletin 2007/10

(21) Application number: 05779995.9

(22) Date of filing: 24.05.2005
(51) International Patent Classification (IPC): 
A61M 37/00(2006.01)
(86) International application number:
PCT/US2005/018331
(87) International publication number:
WO 2005/113059 (01.12.2005 Gazette 2005/48)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
Designated Extension States:
AL BA HR LV MK YU

(30) Priority: 24.05.2004 US 851637
17.02.2005 US 653961 P

(71) Applicants:
  • Panacos Pharmaceuticals, Inc.
    Gaithersburg, MD 20877 (US)
  • THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Rockville, MD 20852 (US)

(72) Inventors:
  • SALZWEDEL, Karl
    Olney, Maryland 20832 (US)
  • LI, Feng
    Gaithersburg, Maryland 20878 (US)
  • WILD, Carl T.
    Gaithersburg, Maryland 20879 (US)
  • ALLAWAY, Graham P.
    Darnestown, Maryland 20878 (US)
  • FREED, Eric O.
    Frederick, Maryland 21702 (US)

(74) Representative: Chapman, Paul William et al
Kilburn & Strode, 20 Red Lion Street
London WC1R 4PJ
London WC1R 4PJ (GB)

   


(54) INHIBITION OF HIV-1 REPLICATION BY DISRUPTION OF THE PROCESSING OF THE VIRAL CAPSID-SPACER PEPTIDE 1 PROTEIN