(19)

(11)

EP 1 765 403 A2

(12)

(43) Date of publication: 28.03.2007 Bulletin 2007/13 (21) Application number: 05780057.5 (22) Date of filing: 05.05.2005

(51) International Patent Classification (IPC):  A61K 39/40(2006.01) (86) International application number: PCT/US2005/015681 (87) International publication number: WO 2005/115457 (08.12.2005 Gazette 2005/49)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR LV MK YU (30) Priority: 10.05.2004 US 569770 P (71) Applicant: University of Utah Research Foundation Salt Lake City, UT 84108 (US)	(72) Inventors: CUCHELKAR, Vaikunth Salt Lake City, UT 84112 (US) KOPECHOVA, Pavla Salt Lake City, UT 84108 (US) PETERSON, C., Matthew Bountiful, UT 84010 (US) KOPECEK, Jindrich Salt Lake City, UT 84108 (US) (74) Representative: van Loon, C.J.J.  c/o VEREENIGDE Johan de Wittlaan 7 2517 JR The Hague 2517 JR The Hague (NL)