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EP 1 765 980 A1

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(43) Date of publication: 28.03.2007 Bulletin 2007/13 (21) Application number: 04756607.0 (22) Date of filing: 02.07.2004

(51) International Patent Classification (IPC):  C12N 5/00(2006.01) (86) International application number: PCT/US2004/021391 (87) International publication number: WO 2006/014156 (09.02.2006 Gazette 2006/06)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (71) Applicant: MacroPore Biosurgery, Inc. San Diego, California 92121 (US)

(72) Inventors: HEDRICK, Marc, H. Encino, CA 91436 (US) FRASER, John, K. Los Angeles, CA 90064 (US) SCHULZKI, Michael, J. San Diego, CA 92121 (US) BYRNES, Bobby San Diego, CA 92121 (US) CARLSON, Grace San Diego, CA 92121 (US) SCHREIBER, Ronda, Elizabeth San Diego, CA 92129 (US) WULUR, Isabella San Diego, CA 92121 (US) (74) Representative: Plougmann & Vingtoft A/S  Sundkrogsgade 9 P.O. Box 831 2100 Copenhagen Ø 2100 Copenhagen Ø (DK)