(19)

(11)

EP 1 765 992 A2

(12)

(43) Date of publication: 28.03.2007 Bulletin 2007/13 (21) Application number: 05758682.8 (22) Date of filing: 03.06.2005

(51) International Patent Classification (IPC):  C12N 9/10(2006.01) (86) International application number: PCT/US2005/019442 (87) International publication number: WO 2005/121331 (22.12.2005 Gazette 2005/51)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR LV MK YU (30) Priority: 03.06.2004 US 546530 P 03.08.2004 US 598584 P (71) Applicant: Neose Technologies, Inc. Horsham, PA 19044 (US)	(72) Inventors: JOHNSON, Karl F. Willow Grove, PA 19090 (US) CHEN, Xi Woodland, CA (US) TAUDTE, Susann  (US) SARIBAS, Sami Philadelphia, PA 19144 (US) (74) Representative: Cripps, Joanna Elizabeth et al Mewburn Ellis LLP York House 23 Kingsway London WC2B 6HP London WC2B 6HP (GB)