(19)

(11)

EP 1 766 019 A2

(12)

(88) Date of publication A3: 16.03.2006 (43) Date of publication: 28.03.2007 Bulletin 2007/13 (21) Application number: 05750867.3 (22) Date of filing: 19.05.2005

(51) International Patent Classification (IPC):  C12N 15/29(2006.01) A01H 5/00(2006.01) C12N 15/82(2006.01) (86) International application number: PCT/US2005/017583 (87) International publication number: WO 2005/112608 (01.12.2005 Gazette 2005/48)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (30) Priority: 21.05.2004 US 573443 P (71) Applicant: Michigan state University Hayward CA 94545 (US)	(72) Inventors: THOMASHOW, Michael East Lansing, Michigan 48823 (US) GILMOUR, Sarah J. Mason, Michigan 48854 (US) COOK, Daniel D. Oxford, Mississippi 38655 (US) CANELLA, Donatella Lansing, Michigan 48910 (US) (74) Representative: Brasnett, Adrian Hugh  Mewburn Ellis LLP York House 23 Kingsway London WC2B 6HP London WC2B 6HP (GB)