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EP 1 766 041 A2

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(43) Date of publication: 28.03.2007 Bulletin 2007/13 (21) Application number: 04753721.2 (22) Date of filing: 27.05.2004

(51) International Patent Classification (IPC):  C12Q 1/00(2006.01) G01N 33/48(2006.01) C12Q 1/68(2006.01) G01N 33/567(2006.01) (86) International application number: PCT/US2004/016940 (87) International publication number: WO 2005/118834 (15.12.2005 Gazette 2005/50)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL HR LT LV MK (71) Applicant: SEQUENOM, INC. San Diego, California 92121 (US)

(72) Inventors: ROTH, Richard, B. La Jolla, CA 92037 (US) NELSON, Matthew, Roberts San Marcos, CA 92069 (US) BRAUN, Andreas San Diego, CA 92130 (US) KAMMERER, Stefan, M. San Diego, CA 92130 (US) RENELAND, Rikard San Diego, CA 92122 (US) ROSETTE, Caridad San Diego, CA 92122 (US) DENISSENKO, Mikhail, F. Poway, CA 92064 (US) EKBLOM, Jonas, Göran San Diego, CA 92130 (US) HOYAL-WRIGHTSON, Carolyn, R. San Diego, CA 92111 (US) (74) Representative: Vossius & Partner  Siebertstrasse 4 81675 München 81675 München (DE)