(19)
(11) EP 1 773 389 A2

(12)

(43) Date of publication:
18.04.2007 Bulletin 2007/16

(21) Application number: 05780060.9

(22) Date of filing: 09.05.2005
(51) International Patent Classification (IPC): 
A61K 39/395(2006.01)
(86) International application number:
PCT/US2005/015981
(87) International publication number:
WO 2005/115454 (08.12.2005 Gazette 2005/49)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
Designated Extension States:
AL BA HR LV MK YU

(30) Priority: 07.05.2004 US 569131 P

(71) Applicants:
  • Massachusetts Institute of Technology
    Cambridge, MA 02139 (US)
  • Medical Research Council
    20 Park Crescent London W1B 1AL (GB)

(72) Inventors:
  • YAFFE, Michael, B.
    West Roxbury, MA 02132 (US)
  • CLAPPERTON, Julie, A.
    London NW4 1JS (GB)
  • MANKE, Isaac, A.
    New York, NY 10005 (US)
  • LOWERY, Drew, M.
    Cambridge, MA 02139 (US)
  • HAIRE, Lesley, F.
    Welwyn Garden City, Herts AL7 2JQ (GB)
  • SMERDON, Stephen, J.
    London N12 7DP (GB)

(74) Representative: Bösl, Raphael Konrad 
Patentanwälte Isenbruck Bösl Hörschler Wichmann Huhn Prinzregentenstrasse 68
81675 München
81675 München (DE)

   


(54) METHODS AND COMPOSITIONS FOR CANCER TREATMENT RELATING TO BRCA1 BRCT DOMAIN RECOGNITION OF PHOSPHORYLATED BACH1