(19)

(11)

EP 1 778 237 A1

(12)

(43) Date of publication: 02.05.2007 Bulletin 2007/18 (21) Application number: 05729386.2 (22) Date of filing: 10.03.2005

(51) International Patent Classification (IPC):  A61K 31/519(2006.01) A61P 35/00(2006.01) A61P 29/02(2006.01) A61P 35/02(2006.01) (86) International application number: PCT/US2005/008271 (87) International publication number: WO 2005/089767 (29.09.2005 Gazette 2005/39)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (30) Priority: 12.03.2004 US 552787 P 09.03.2005 US 78614 (71) Applicant: Syntrix Biosystems, Inc. Auburn WA 98001 (US)	(72) Inventors: Kamen, Barton New Brunswick, NJ 08903 (US) Cole, Peter New Brunswick, NJ 08903 (US) Smith, Angela New Brunswick, NJ 08903 (US) Zebala, John A. Auburn, WA 98001 (US) (74) Representative: Jorio, Paolo  Studio Torta S.r.l. Via Viotti, 9 10121 Torino 10121 Torino (IT)