(19)

(11)

EP 1 781 269 A2

(12)

(43) Date of publication: 09.05.2007 Bulletin 2007/19 (21) Application number: 05821176.4 (22) Date of filing: 19.05.2005

(51) International Patent Classification (IPC):  A61K 31/00(2006.01) (86) International application number: PCT/IB2005/003950 (87) International publication number: WO 2006/048781 (11.05.2006 Gazette 2006/19)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR LV MK YU (30) Priority: 20.05.2004 US 572821 P (71) Applicants: St. Mary's Hospital NHS Trust Praed Street London W2 1NY (GB) IMPERIAL COLLEGE INNOVATIONS LIMITED London SW7 2AZ (GB)	(72) Inventors: LACK, G. Dr., Paediatric Allergy & Immunology London W2 1NY (GB) TURCANU, V. Dr., Imperial College London London W21PG (GB) (74) Representative: Peter, Beate et al Mintz Levin Cohn Ferris Glovsky and Popeo Intellectual Property LLP The Rectory, 9 Ironmonger Lane London EC2V 8EY London EC2V 8EY (GB)