(19)

(11)

EP 1 782 451 A2

(12)

(43) Date of publication: 09.05.2007 Bulletin 2007/19 (21) Application number: 05802881.2 (22) Date of filing: 30.06.2005

(51) International Patent Classification (IPC):  H01J 49/00(2006.01) H01J 1/50(2006.01) (86) International application number: PCT/US2005/023607 (87) International publication number: WO 2006/014374 (09.02.2006 Gazette 2006/06)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR LV MK YU (30) Priority: 01.07.2004 US 585349 P (71) Applicant: Ciphergen Biosystems, Inc. Fremont, CA 94555 (US)	(72) Inventor: KELLER, Craig A. Menlo Park, California 94025 (US) (74) Representative: Leeming, John Gerard  J.A. Kemp & Co., 14 South Square, Gray's Inn London WC1R 5JJ London WC1R 5JJ (GB)