(19)

(11)

EP 1 786 802 A1

(12)

(43) Date of publication: 23.05.2007 Bulletin 2007/21 (21) Application number: 05789340.6 (22) Date of filing: 24.08.2005

(51) International Patent Classification (IPC):  C07D 401/14(2006.01) A61P 35/00(2006.01) C07D 403/14(2006.01) A61K 31/506(2006.01) C07D 405/14(2006.01) C07D 471/04(2006.01) (86) International application number: PCT/US2005/030133 (87) International publication number: WO 2006/026306 (09.03.2006 Gazette 2006/10)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) Priority: 31.08.2004 US 606045 P (71) Applicant: Biogen Idec MA, Inc. Cambridge Massachusetts 02142 (US)	(72) Inventors: LEE, Wen-Cherng Lexington, MA 02421 (US) SUN, Lihong Arlington, MA 02474 (US) CHUAQUI, Claudio Somerville, MA 02144 (US) SINGH, Juswinder Ashland, MA 01721 (US) SHAN, Feng Braintree, MA 02184 (US) (74) Representative: Vossius & Partner  Siebertstrasse 4 81675 München 81675 München (DE)