(19)

(11)

EP 1 789 047 A2

(12)

(43) Date of publication: 30.05.2007 Bulletin 2007/22 (21) Application number: 05796339.9 (22) Date of filing: 06.09.2005

(51) International Patent Classification (IPC):  A61K 31/485(2006.01) (86) International application number: PCT/US2005/031737 (87) International publication number: WO 2006/029167 (16.03.2006 Gazette 2006/11)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK YU (30) Priority: 08.09.2004 US 936431 (71) Applicant: Jenken Biosciences, Inc. Research Triangle Park, NC 27709 (US)	(72) Inventor: WU, Edwin, S., C. Cary, NC 27513 (US) (74) Representative: Ebner von Eschenbach, Jennifer et al Ladas & Parry LLP Dachauerstrasse 37 80335 München 80335 München (DE)