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(11)

EP 1 789 072 A2

(12)

(43) Date of publication: 30.05.2007 Bulletin 2007/22 (21) Application number: 05856585.4 (22) Date of filing: 29.03.2005

(51) International Patent Classification (IPC):  A61K 38/17(2006.01) C12N 1/21(2006.01) C12N 15/74(2006.01) C07K 14/47(2006.01) C12P 21/06(2006.01) (86) International application number: PCT/US2005/010732 (87) International publication number: WO 2006/073417 (13.07.2006 Gazette 2006/28)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR LV MK YU (30) Priority: 10.05.2004 US 842179 10.05.2004 US 842206 22.09.2004 US 613013 P 03.11.2004 US 980459 (71) Applicant: Curagen Corporation New Haven, CT 06511 (US)	(72) Inventors: ALVAREZ, Enrique Clinton, CT 06413 (US) HAHNE, William Madison, CT 06443 (US) MACLACHLAN, Timothy, K. Cheshire, CT 06410 (US) NARAYANAN, Bisni New Haven, CT 06510 (US) (74) Representative: Peter, Beate et al Mintz Levin Cohn Ferris Glovsky and Popeo Intellectual Property LLP The Rectory, 9 Ironmonger Lane London EC2V 8EY London EC2V 8EY (GB)