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(11)

EP 1 789 549 A1

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(43) Date of publication: 30.05.2007 Bulletin 2007/22 (21) Application number: 05766513.5 (22) Date of filing: 14.07.2005

(51) International Patent Classification (IPC):  C12N 15/11(2006.01) A61P 35/00(2006.01) A61K 31/713(2006.01) (86) International application number: PCT/JP2005/013444 (87) International publication number: WO 2006/013733 (09.02.2006 Gazette 2006/06)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) Priority: 05.08.2004 US 598834 P (71) Applicants: The University of Tokyo Bunkyo-Ku, Tokyo 113-8654 (JP) Oncotherapy Science, Inc. Kawasaki-shi, Kanagawa 213-0012 (JP)	(72) Inventors: NAKAMURA, Yusuke, The University of Tokyo Tokyo 1138654 (JP) KATAGIRI, Toyomasa, The University of Tokyo Tokyo 1138654 (JP) FUKUKAWA, Chikako, The University of Tokyo Tokyo 1138654 (JP) (74) Representative: Woods, Geoffrey Corlett  J.A. KEMP & CO. Gray's Inn 14 South Square London WC1R 5JJ London WC1R 5JJ (GB)