(19)
(11) EP 1 789 552 A2

(12)

(88) Date of publication A3:
14.09.2006

(43) Date of publication:
30.05.2007 Bulletin 2007/22

(21) Application number: 05783932.6

(22) Date of filing: 10.08.2005
(51) International Patent Classification (IPC): 
C12N 15/11(2006.01)
A61K 35/76(2006.01)
G01N 33/574(2006.01)
 A61K 38/18(2006.01)
A61K 31/00(2006.01)
A61P 35/02(2006.01)
(86) International application number:
PCT/US2005/028362
(87) International publication number:
WO 2006/020684 (23.02.2006 Gazette 2006/08)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

(30) Priority: 10.08.2004 US 600132 P

(71) Applicant: Institute for Multiple Myeloma and Bone Cancer Research
West Hollywood, CA 90069 (US)

(72) Inventors:
  • BERENSON, James
    Beverly Hills, California 90210 (US)
  • HAIMING, Chen
    Los Angeles, California 90036 (US)
  • GORDON, Melinda S.
    Los Angeles, California 90035 (US)

(74) Representative: Viering, Jentschura & Partner 
Postfach 22 14 43
80504 München
80504 München (DE)

   


(54) METHODS OF REGULATING DIFFERENTIATION AND TREATING OF MULTIPLE MYELOMA