| (19) |
 |
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(11) |
EP 1 790 351 A8 |
| (12) |
CORRECTED EUROPEAN PATENT APPLICATION |
|
published in accordance with Art. 158(3) EPC |
| (15) |
Correction information: |
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Corrected version no 1 (W1 A1) |
| (48) |
Corrigendum issued on: |
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10.10.2007 Bulletin 2007/41 |
| (43) |
Date of publication: |
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30.05.2007 Bulletin 2007/22 |
| (22) |
Date of filing: 12.09.2005 |
|
| (51) |
International Patent Classification (IPC):
|
| (86) |
International application number: |
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PCT/JP2005/016739 |
| (87) |
International publication number: |
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WO 2006/030730 (23.03.2006 Gazette 2006/12) |
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| (84) |
Designated Contracting States: |
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AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE
SI SK TR |
| (30) |
Priority: |
15.09.2004 JP 2004268891
|
| (71) |
Applicant: OTSUKA PHARMACEUTICAL CO., LTD. |
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Chiyoda-ku
Tokyo 101-8535 (JP) |
|
| (72) |
Inventors: |
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- YAMAMOTO, Akira
Kyoto-shi, Kyoto 6068344 (JP)
- YAMADA, Keigo
c/o Formulation Research Institute of
OTSUKA PHARMACEUTICAL CO., LTD.,
Tokushima-shi, Tokushima 7710182 (JP)
|
| (74) |
Representative: HOFFMANN EITLE |
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Patent- und Rechtsanwälte
Arabellastrasse 4
81925 München
81925 München (DE) |
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| |
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| (54) |
PERMUCOSAL COMPOSITION AND METHOD OF IMPROVING PERMUCOSAL ABSORPTION |
(57) An object of the invention is to provide a composition for transmucosal administration
that enables pharmacologically active peptides and proteins to be efficiently absorbed
through the mucosa such as the pulmonary mucosa, nasal mucosa, oral mucosa, vaginal
mucosa, gastric mucosa, gastrointestinal mucosa or the like.
A composition for transmucosal administration are prepared by adding (i) at least
one member selected from the group consisting of peptides and proteins having pharmacological
activity; and (ii) at least one member selected from the group consisting of chitosan
oligosaccharides having a polymerization degree of from 2 to 20, derivatives thereof,
glucosamine, and salts thereof.