| (19) |
 |
|
(11) |
EP 1 792 995 A3 |
| (12) |
EUROPEAN PATENT APPLICATION |
| (88) |
Date of publication A3: |
|
13.06.2007 Bulletin 2007/24 |
| (43) |
Date of publication A2: |
|
06.06.2007 Bulletin 2007/23 |
| (22) |
Date of filing: 08.05.2001 |
|
| (51) |
International Patent Classification (IPC):
|
|
| (84) |
Designated Contracting States: |
|
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
Designated Extension States: |
|
AL LT LV MK RO SI |
| (30) |
Priority: |
08.05.2000 US 202672 P
30.05.2000 US 207852
16.06.2000 US 211801
16.06.2000 US 212044
16.06.2000 US 211797
16.06.2000 US 211796
16.06.2000 US 211798
26.09.2000 US 235335
26.09.2000 US 235361
26.09.2000 US 235398
|
| (62) |
Application number of the earlier application in accordance with Art. 76 EPC: |
|
01931274.3 / 1282718 |
| (71) |
Applicant: Sanofi Pasteur Limited |
|
Toronto,
Ontario M2R 3T4 (CA) |
|
| (72) |
Inventors: |
|
- Murdin, Andrew D.
Richmond Hill
Ontario L4B 3C2 (CA)
- Oomen, Raymond P.
Aurora
Ontario L4G 2L6 (CA)
- Wang, Joe
Toronto
Ontario M2H 2E8 (CA)
- Dunn, Pamela
Woodbridge
Ontario L4L 3Z1 (CA)
|
| (74) |
Representative: Desaix, Anne et al |
|
Ernest Gutmann - Yves Plasseraud S.A.S.
3, rue Auber
75009 Paris
75009 Paris (FR) |
|
| |
|
| (54) |
Chlamydia secretory locus orf and uses thereof |
(57) The present invention provides nucleic acids, proteins and vectors for a method of
nucleic acid, including DNA, immunization of a host, including humans, against disease
caused by infection by a strain of
Chlamydia, specifically
C.
pneumoniae. The method employs a vector containing a nucleotide sequence encoding a polypeptide
of a strain of
Chlamydia pneumoniae operably linked to a promoter to effect expression of the gene product in the host.
The polypeptides are derived from
C.
pneumoniae and are selected from an ATP-binding cassette protein, a secretory locus ORF, an
endopeptidase, a protease, a metalloprotease, CLP protease ATPase, a CLP protease
subunit, a translycolase/transpeptidase, a CLPc protease and thioredoxin.