(19)

(11)

EP 1 794 298 A2

(12)

(88) Date of publication A3: 08.12.2005 (43) Date of publication: 13.06.2007 Bulletin 2007/24 (21) Application number: 05729379.7 (22) Date of filing: 21.03.2005

(51) International Patent Classification (IPC):  C12N 15/31(2006.01) C12N 15/75(2006.01) C12P 21/04(2006.01) C12R 1/07(2006.01) C07K 7/56(2006.01) C12N 1/21(2006.01) C07K 14/32(2006.01) C12N 15/09(2006.01) C12N 5/10(2006.01) (86) International application number: PCT/GB2005/001055 (87) International publication number: WO 2005/093069 (06.10.2005 Gazette 2005/40)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (30) Priority: 26.03.2004 GB 0406870 (71) Applicant: Novacta Biosystems Limited Hatfield Hertfordshire AL10 9AB (GB)

(72) Inventors: Dawson, Michael John, Novacta Biosystems Ltd Hatfield Hertfordshire AL10 9AB (GB) Cortes Bargallo, Jesus, Novacta Biosystems Ltd. Hatfield Hertfordshire AL10 9AB (GB) Rudd, Brian Arthur Michael, Novacta Biosystems Ltd Hatfield Hertfordshire AL10 9AB (GB) Boakes, Steven, Novacta Biosystems Ltd Hatfield Hertfordshire AL10 9AB (GB) Bierbaum, Gabriele, Inst. für Mediz. Mikro. und 53105 Bonn (DE) Hoffmann, Anja 53119 Bonn (DE) Schmitz, Stephanie, Inst. für Mediz. Mikro. und 53105 Bonn (DE) (74) Representative: Brasnett, Adrian Hugh et al Mewburn Ellis LLP York House 23 Kingsway London WC2B 6HP London WC2B 6HP (GB)