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(11)

EP 1 797 075 A1

(12)

(43) Date of publication: 20.06.2007 Bulletin 2007/25 (21) Application number: 05784659.4 (22) Date of filing: 22.09.2005

(51) International Patent Classification (IPC):  C07D 405/06(2006.01) A61K 31/454(2006.01) A61P 25/00(2006.01) A61P 25/22(2006.01) A61P 35/00(2006.01) C07D 405/14(2006.01) A61K 31/4184(2006.01) A61P 1/00(2006.01) A61P 25/16(2006.01) A61P 25/28(2006.01) A61P 9/00(2006.01) (86) International application number: PCT/SE2005/001401 (87) International publication number: WO 2006/033629 (30.03.2006 Gazette 2006/13)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) Priority: 24.09.2004 WO PCT/GB2004/004112 24.09.2004 WO PCT/GB2004/004126 28.02.2005 SE 0500453 (71) Applicant: AstraZeneca AB S-151 85 Södertälje (SE)	(72) Inventors: LIU, Ziping St. Laurent, Québec H4S 1Z9 (CA) PAGÈ, Daniel St. Laurent, Québec H4S 1Z9 (CA) TREMBLAY, Maxime St. Laurent, Québec H4S 1Z9 (CA) WALPOLE, Christopher St. Laurent, Québec H4S 1Z9 (CA) YANG, Hua St. Laurent, Québec H4S 1Z9 (CA) (74) Representative: Wahlström, Stig Christer Gunnar et al AstraZeneca Global Intellectual Property 151 85 Södertälje 151 85 Södertälje (SE)