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EP 1 797 092 A1

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(43) Date of publication: 20.06.2007 Bulletin 2007/25 (21) Application number: 05779103.0 (22) Date of filing: 07.09.2005

(51) International Patent Classification (IPC):  C07D 473/00(2006.01) A61K 31/52(2006.01) A61P 29/00(2006.01) C07D 473/40(2006.01) A61P 35/02(2006.01) (86) International application number: PCT/EP2005/054404 (87) International publication number: WO 2006/027365 (16.03.2006 Gazette 2006/11)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: HR (30) Priority: 09.09.2004 EP 04104344 09.09.2004 US 608147 P (71) Applicant: Solvay Pharmaceuticals B.V. 1381 CP Weesp (NL)

(72) Inventors: KOCH, Melle, Solvay Pharmaceuticals B.V. 1381 CP WEESP (NL) DEN HARTOG, Jacobus A.J. 1381 CP WEESP (NL) KOOMEN, Gerrit-Jan, Solvay Pharmaceuticals B.V. 1381 CP WEESP (NL) WANNER, Martinus J., Solvay Pharmaceuticals B.V 1381 CP WEESP (NL) FEENSTRA, Roelof W., Solvay Pharmaceuticals B.V 1381 CP WEESP (NL) (74) Representative: Hogenbirk, Marijke et al Octrooibureau Zoan B.V. P.O. Box 140 NL-1380 AC Weesp NL-1380 AC Weesp (NL)