(19)

(11)

EP 1 802 961 A2

(12)

(88) Date of publication A3: 08.02.2007 (43) Date of publication: 04.07.2007 Bulletin 2007/27 (21) Application number: 05798023.7 (22) Date of filing: 08.09.2005

(51) International Patent Classification (IPC):  G01N 24/00(2006.01) (86) International application number: PCT/US2005/031972 (87) International publication number: WO 2006/039077 (13.04.2006 Gazette 2006/15)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK YU (30) Priority: 29.09.2004 US 614509 P (71) Applicant: Ciphergen Biosystems, Inc. Fremont, CA 94555 (US)	(72) Inventors: HUANG, Wenxi Fremont, CA 94539 (US) ROTH, Steve Gilroy, CA 95020 (US) (74) Representative: Harrison Goddard Foote  Belgrave Hall Belgrave Street Leeds LS2 8DD Leeds LS2 8DD (GB)