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(11)

EP 1 804 584 A2

(12)

(88) Date of publication A3: 24.08.2006 (43) Date of publication: 11.07.2007 Bulletin 2007/28 (21) Application number: 05810080.1 (22) Date of filing: 14.10.2005

(51) International Patent Classification (IPC):  A01N 65/00(2006.01) (86) International application number: PCT/US2005/036961 (87) International publication number: WO 2006/044616 (27.04.2006 Gazette 2006/16)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) Priority: 14.10.2004 US 619263 P (71) Applicant: Academia Sinica Nan-Kang, Taipei (TW)

(72) Inventors: WONG, Chi-Huey CA 92067 (US) HSU, Hsien-Yeh Shihlin District, Taipei, 111 (TW) HUA, Kuo-Feng Taoyuan County 320 (TW) LIN, Chun-Hung Tapei, 106 (TW) HSU, Jason New York, NY 10021 (US) CHEN, Shui-Tein Taipei, 105 (TW) LIN, Kuo-I Da-an District, Taipei, 106 (TW) YANG, Wen-Bin Nankang District, Taipei, 115 (TW) YU, John CA 92037 (US) YU, Alice CA 92037 (US) (74) Representative: Wallis, Helen Frances Mary et al Olswang 90 High Holborn London WC1V 6XX London WC1V 6XX (GB)