(19)

(11)

EP 1 809 334 A2

(12)

(88) Date of publication A3: 26.04.2007 (43) Date of publication: 25.07.2007 Bulletin 2007/30 (21) Application number: 05811041.2 (22) Date of filing: 09.11.2005

(51) International Patent Classification (IPC):  A61K 47/48(2006.01) A61P 31/18(2006.01) C07K 7/06(2006.01) A61P 35/00(2006.01) (86) International application number: PCT/EP2005/011991 (87) International publication number: WO 2006/050930 (18.05.2006 Gazette 2006/20)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK YU (30) Priority: 12.11.2004 EP 04026934 (71) Applicant: Xigen S.A. 1003 Lausanne (CH)	(72) Inventors: BONNY, Christophe CH-1006 Lausanne (CH) COQUOZ, Didier CH-1025 St. Sulpice (CH) CHEN, Jianhua CH-1010 Lausanne (CH) (74) Representative: Graf von Stosch, Andreas et al Bosch, Graf v. Stosch, Jehle Patentanwaltsgesellschaft mbH Flüggenstrasse 13 D-80639 München D-80639 München (DE)