| (84) |
Designated Contracting States: |
|
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
| (30) |
Priority: |
22.02.1999 US 121133 P
|
| (43) |
Date of publication of application: |
|
25.07.2007 Bulletin 2007/30 |
| (62) |
Application number of the earlier application in accordance with Art. 76 EPC: |
|
00915818.9 / 1154756 |
| (73) |
Proprietors: |
|
- Georgetown University
Washington, DC 20057 (US)
- SynerGene Therapeutics, Inc.
Potomac, MD 20854-3963 (US)
|
|
| (72) |
Inventors: |
|
- Alexander, William
Rockville, MD 20851 (US)
- Xu, Liang
Ann Arbor, MI 48103-8818 (US)
- Huang, Cheng-Cheng
Fairfax, VA 22031-3021 (US)
- Tang, WenHua
Ann Arbor, MI 48103-8818 (US)
- Chang, Esther H.
Potomoac, MD 20854-4438 (US)
|
| (74) |
Representative: Daniels, Jeffrey Nicholas et al |
|
Page White & Farrer
Bedford House
John Street
London WC1N 2BF
London WC1N 2BF (GB) |
| (56) |
References cited: :
WO-A-99/25320
WO-A1-99/25320
|
WO-A1-00/15649
|
|
| |
|
|
- HAMADA K ET AL: "Adenovirus-mediated transfer of HPV 16 E6/E7 antisense RNA to human
cervical cancer cells" GYNECOLOGIC ONCOLOGY 1996 UNITED STATES, vol. 63, no. 2, 1996,
pages 219-227, XP002437975 ISSN: 0090-8258
- DATABASE MEDLINE [Online] US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US;
March 1994 (1994-03), ZHANG W W ET AL: "High-efficiency gene transfer and high-level
expression of wild-type p53 in human lung cancer cells mediated by recombinant adenovirus."
XP002437978 Database accession no. NLM7621238 & CANCER GENE THERAPY MAR 1994, vol.
1, no. 1, March 1994 (1994-03), pages 5-13, ISSN: 0929-1903
- HAMADA K ET AL: "Growth inhibition of human cervical cancer cells with the recombinant
adenovirus p53 in vitro." GYNECOLOGIC ONCOLOGY MAR 1996, vol. 60, no. 3, March 1996
(1996-03), pages 373-379, XP002437976 ISSN: 0090-8258
- XU L ET AL: "Transferrin-liposome-mediated p53 sensitization of squamous cell carcinoma
of the head and neck to radiation in vitro" HUMAN GENE THERAPY, MARY ANN LIEBERT,
NEW YORK ,NY, US, vol. 8, no. 4, 1 March 1997 (1997-03-01), pages 467-475, XP002098089
ISSN: 1043-0342
- DE KRUIF J ET AL: "Biosynthetically lipid-modified human scFv fragments from phage
display libraries as targeting molecules for immunoliposomes" FEBS LETTERS, ELSEVIER,
AMSTERDAM, NL, vol. 3, no. 399, 16 December 1996 (1996-12-16), pages 232-236, XP002075140
ISSN: 0014-5793
- COMPAGNON B ET AL: "ENHANCED GENE DELIVERY AND EXPRESSION IN HUMAN HEPATOCELLULAR
CARCINOMA CELLS BY CATIONIC IMMUNOLIPOSOMES" JOURNAL OF LIPOSOME RESEARCH, TAYLOR
& FRANCIS, PHILADELPHIA, PA, US, vol. 7, no. 1, 1997, pages 127-141, XP000682912 ISSN:
0898-2104
- YOSHIDA J ET AL: "SIMPLE PREPARATION AND CHARACTERIZATION OF CATIONIC LIPOSOMES ASSOCIATED
WITH A MONOCLONAL ANTIBODY AGAINST GLIOMA-ASSOCIATED ANTIGEN (IMMUNOLIPOSOMES)" JOURNAL
OF LIPOSOME RESEARCH, TAYLOR & FRANCIS, PHILADELPHIA, PA, US, vol. 5, no. 4, January
1995 (1995-01), pages 981-995, XP000558625 ISSN: 0898-2104
- KOBATAKE E ET AL: "A FLUOROIMMUNOASSAY BASED ON IMMUNOLIPOSOMES CONTAINING GENETICALLYENGINEERED
LIPID-TAGGED ANTIBODY" ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. COLUMBUS,
US, vol. 69, no. 7, 1 April 1997 (1997-04-01), pages 1295-1298, XP000689729 ISSN:
0003-2700
- JIANG A ET AL: "Cell-type-specific gene transfer into human cells with retroviral
vectors that display single-chain antibodies" JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY
FOR MICROBIOLOGY, US, vol. 72, no. 12, December 1998 (1998-12), pages 10148-10156,
XP002103152 ISSN: 0022-538X
- CELL, vol. 45, 1986, pages 229-236,
- 'MOLECULAR BIOLOGY AND BIOTECHNOLOGY. ED: MEYERS', WILEY-VCH page 609
- 'VIROLOGY ED: FIELDS', RAVEN PRESS pages 210 - 212
- MICROBIOLOGICAL REVIEWS, vol. 46, 1982, pages 377-383,
|
|
