TWEAK AS A THERAPEUTIC TARGET FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES ASSOCIATED WITH CEREBRAL EDEMA AND AND CELL DEATH - Patent 1811838

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EP 1 811 838 A2

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(88)	Date of publication A3:
	03.08.2006

(43)	Date of publication:
	01.08.2007 Bulletin 2007/31

(21)	Application number: 05848068.2

(22)	Date of filing: 08.11.2005

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International Patent Classification (IPC):

A01N 37/18^(2006.01)
A61K 38/00^(2006.01)
A61K 31/70^(2006.01)
A61K 39/42^(2006.01)
A61K 39/385^(2006.01)

A01N 43/04^(2006.01)
A61K 38/16^(2006.01)
A61K 38/40^(2006.01)
A61K 39/395^(2006.01)

(86)	International application number:
	PCT/US2005/040360

(87)	International publication number:
	WO 2006/052926 (18.05.2006 Gazette 2006/20)

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
	Designated Extension States:
	AL BA HR MK YU

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Priority:

08.11.2004 US 626054 P
13.12.2004 US 636024 P

(71)	Applicant: University of Maryland, Baltimore
	Baltimore, MD 21201-1627 (US)

(72)	Inventors:
	WINKLES, Jeffrey, A. Fraderick, MD 21701-5892 (US) YEPES, Manuel, S. Atlanta, GA 30306-2225 (US)

(74)	Representative: Leman Consulting S.A.
	Chemin de Précossy 31 CH-1260 Nyon CH-1260 Nyon (CH)

(54)	TWEAK AS A THERAPEUTIC TARGET FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES ASSOCIATED WITH CEREBRAL EDEMA AND AND CELL DEATH