(19)
(11) EP 1 812 023 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
26.12.2012 Bulletin 2012/52

(45) Mention of the grant of the patent:
01.08.2012 Bulletin 2012/31

(21) Application number: 05795238.4

(22) Date of filing: 17.10.2005
(51) International Patent Classification (IPC): 
A61K 35/74(2006.01)
A61P 31/00(2006.01)
(86) International application number:
PCT/EP2005/011152
(87) International publication number:
WO 2006/045475 (04.05.2006 Gazette 2006/18)

(54)

LACTIC ACID BACTERIA AS PROBIOTIC STRAINS AND COMPOSITIONS CONTAINING SAME

MILCHSÄURE-BAKTERIEN ALS PROBIOTISCHE STÄMME UND DIESE ENTHALTENDE ZUSAMMENSETZUNGEN

BACTERIES LACTIQUES UTILISEES COMME SOUCHES PROBIOTIQUES ET COMPOSITIONS LES CONTENANT


(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

(30) Priority: 22.10.2004 WO PCT/EP2004/011980
22.10.2004 WO PCT/EP2004/011981
10.02.2005 WO PCT/EP2005/001354

(43) Date of publication of application:
01.08.2007 Bulletin 2007/31

(60) Divisional application:
12178634.7

(73) Proprietor: Graf, Federico, Dr.
8032 Zürich (CH)

(72) Inventors:
  • GRAF, Federico
    CH-8050 Zürich (CH)
  • GROB, Philipp
    CH-8050 Zürich (CH)
  • BRASSART, Dominique
    CH-1022 Chavannes/Renens (CH)

(74) Representative: HOFFMANN EITLE 
Patent- und Rechtsanwälte Arabellastrasse 4
81925 München
81925 München (DE)


(56) References cited: : 
EP-A- 0 956 858
WO-A-03/080813
US-A- 6 093 394
WO-A-90/09398
US-A- 5 645 830
   
  • BORIS S ET AL: "Adherence of human vaginal lactobacilli to vaginal epithelial cells and interaction with uropathogens" INFECTION AND IMMUNITY, AMERICAN SOCIETY FOR MICROBIOLOGY. WASHINGTON, US, vol. 66, no. 5, May 1998 (1998-05), pages 1985-1989, XP002958494 ISSN: 0019-9567
  • OCANA V ET AL: "ADHESION OF LACTOBACILLUS VAGINAL STRAINS WITH PROBIOTIC PROPERTIES TO VAGINAL EPITHELIAL CELLS" BIOCELL, INSTITUTO DE HISTOLOGIA EMBRIOLOGIA, FACULTAD DE CIENCIAS,, AR, vol. 25, no. 3, 2001, pages 265-273, XP001115002 ISSN: 0327-9545
  • TODORIKI K ET AL: "Inhibition of adhesion of food-borne pathogens to Caco-2 cells by Lactobacillus strains" JOURNAL OF APPLIED MICROBIOLOGY, vol. 91, no. 1, July 2001 (2001-07), pages 154-159, XP002332588 ISSN: 1364-5072
  • GRANATO, DOMINIQUE ET AL: "Cell surface-associated lipoteichoic acid acts as an adhesion factor for attachment of Lactobacillus johnsonii La1 to human enterocyte-like caco-2 cells" APPLIED AND ENVIRONMENTAL MICROBIOLOGY , 65(3), 1071-1077 CODEN: AEMIDF; ISSN: 0099-2240, 1999, XP002332589
  • PFEIFER A ET AL: "Immunological effect of probiotic food" MONATSSCHRIFT FUR KINDERHEILKUNDE 1998 GERMANY, vol. 146, no. 8 SUPPL. 1, 1998, pages S13-S20, XP009049233 ISSN: 0026-9298
  • DATABASE CA [Online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2003, BRASSART, D.: "L. acidophilus NCFM: functional properties of a unique probiotic strain" XP002332655 retrieved from STN Database accession no. 140:162498 & INTERNATIONAL DAIRY FEDERATION [SPECIAL ISSUE] S.I. , 0301(FERMENTED MILK), 136-143 CODEN: IDFSEO; ISSN: 1025-8515, 2003,
  • DATABASE BIOSIS [Online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; March 2004 (2004-03), HUANG CANGHAI ET AL: "Effects of Lactobacilli on the performance, diarrhea incidence, VFA concentration and gastrointestinal microbial flora of weaning pigs." XP002332656 Database accession no. PREV200400233250 & ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES, vol. 17, no. 3, March 2004 (2004-03), pages 401-409, ISSN: 1011-2367
  • DATABASE CA [Online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 1999, MICHETTI, PIERRE ET AL: "Effect of whey-based culture supernatant of Lactobacillus acidophilus (johnsonii) La1 on Helicobacter pylori infection in humans" XP002332657 retrieved from STN Database accession no. 131:17350 & DIGESTION , 60(3), 203-209 CODEN: DIGEBW; ISSN: 0012-2823, 1999,
  • PERDIGON ET AL.: 'Interaction of lactic acid bacteria with the gut immune system.' EUROPEAN JOURNAL OF CLINICAL NUTRITION vol. 56, no. SUPPL 4, pages S21 - S26
 
Remarks:
The file contains technical information submitted after the application was filed and not included in this specification
 
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).