(19)

(11)

EP 1 814 903 A2

(12)

(88) Date of publication A3: 20.07.2006 (43) Date of publication: 08.08.2007 Bulletin 2007/32 (21) Application number: 05803576.7 (22) Date of filing: 15.11.2005

(51) International Patent Classification (IPC):  C07K 14/435(2006.01) C07K 14/16(2006.01) C12N 15/00(2006.01) A61K 39/00(2006.01) (86) International application number: PCT/GB2005/004390 (87) International publication number: WO 2006/051333 (18.05.2006 Gazette 2006/20)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK YU (30) Priority: 15.11.2004 GB 0425197 (71) Applicant: ARES TRADING S.A. 1170 Aubonne (CH)	(72) Inventors: MICHALOVICH, David, Inpharmatica Limited London W1T 2NU (GB) WHITE, Simon, John, Inpharmatica Limited London W1T 2NU (GB) YORKE, Melanie CH-1232 Confignon (CH) MAUNDRELL, Kinsey CH-1224 Geneva (CH) (74) Representative: Goodfellow, Hugh Robin et al Carpmaels & Ransford, 43-45 Bloomsbury Square London WC1A 2RA London WC1A 2RA (GB)