GENE TRAP CASSETTES FOR RANDOM AND TARGETED CONDITIONAL GENE INACTIVATION

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EP 1 815 001 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	23.03.2011 Bulletin 2011/12

(45)	Mention of the grant of the patent:
	02.02.2011 Bulletin 2011/05

(21)	Application number: 05813398.4

(22)	Date of filing: 28.11.2005

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International Patent Classification (IPC):

C12N 15/90^(2006.01)
C12N 5/10^(2006.01)

A01K 67/027^(2006.01)

(86)	International application number:
	PCT/EP2005/056282

(87)	International publication number:
	WO 2006/056617 (01.06.2006 Gazette 2006/22)

(54)	GENE TRAP CASSETTES FOR RANDOM AND TARGETED CONDITIONAL GENE INACTIVATION GEN-FALLEN-KASSETTE FÜR EINE GERICHTETE UND UNGERICHTETE KONDITIONELLE GENINAKTIVIERUNG CASSETTES DE PIEGE A GENES POUR L'INACTIVATION GENETIQUE CONDITIONNELLE ALEATOIRE ET CIBLEE

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

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Priority:

26.11.2004 EP 04028194
18.04.2005 EP 05103092

(43)	Date of publication of application:
	08.08.2007 Bulletin 2007/32

(73)	Proprietors:
	Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) 85764 Neuherberg (DE) MPG Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. 80539 München (DE)

(72)	Inventors:
	VON MELCHNER, Harald 61476 Kronberg/Taunus (DE) SCHNÜTGEN, Frank 63755 Alzenau (DE) WURST, Wolfgang 80937 München (DE) RUIZ, Patricia 10437 Berlin (DE) DE-ZOLT, Silke 63517 Rodenbach (DE) FLOSS, Thomas 85406 Oberappersdorf (DE) HANSEN, Jens 85551 Kirchheim (DE)

(74)	Representative: von Kreisler Selting Werner
	Deichmannhaus am Dom Bahnhofsvorplatz 1 50667 Köln 50667 Köln (DE)

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References cited: :

WO-A-02/40685

WO-A-02/088353

SCHNUETGEN FRANK ET AL: "A directional strategy for monitoring Cre-mediated recombination at the cellular level in the mouse." NATURE BIOTECHNOLOGY, vol. 21, no. 5, May 2003 (2003-05), pages 562-565, XP001206846 ISSN: 1087-0156
LAUTH MATTHIAS ET AL: "Stable and efficient cassette exchange under non-selectable conditions by combined use of two site-specific recombinases." NUCLEIC ACIDS RESEARCH. 1 NOV 2002, vol. 30, no. 21, 1 November 2002 (2002-11-01), pages E115.1-E115.7, XP002332394 ISSN: 1362-4962
JONES JULIE R ET AL: "Strategies for the use of site-specific recombinases in genome engineering." METHODS IN MOLECULAR MEDICINE. 2004, vol. 103, 2004, pages 245-258, XP001206857 ISSN: 1543-1894
HARALD VON MELCHNER ET AL: "Engineering of ES cell genomes with recombinase systems" HANDBOOK OF STEM CELLS, ACADEMIC PRESS, US, vol. 1, 2004, pages 609-622, XP001206845

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).