(19)

(11)

EP 1 819 332 A2

(12)

(88) Date of publication A3: 17.08.2006 (43) Date of publication: 22.08.2007 Bulletin 2007/34 (21) Application number: 05821654.0 (22) Date of filing: 02.12.2005

(51) International Patent Classification (IPC):  A61K 31/437(2006.01) A61P 3/10(2006.01) C07K 5/097(2006.01) A61K 38/06(2006.01) A61K 31/4375(2006.01) C07K 5/078(2006.01) A61K 38/05(2006.01) (86) International application number: PCT/GB2005/050233 (87) International publication number: WO 2006/059164 (08.06.2006 Gazette 2006/23)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK YU (30) Priority: 02.12.2004 US 632461 P (71) Applicant: Prosidion Limited Oxford, Oxfordshire OX4 6LT (GB)	(72) Inventors: KRULLE, Thomas Martin Oxford, Oxfordshire OX4 6LT (GB) ROWLEY, Robert John Oxford, Oxfordshire OX4 6LT (GB) THOMAS, Gerard Hugh Oxford, Oxfordshire OX4 6LT (GB) (74) Representative: Blakey, Alison Jane et al Prosidion Limited Windrush Court Watlington Road Oxford OX4 6LT Oxford OX4 6LT (GB)