(19)

(11)

EP 1 824 468 A2

(12)

(88) Date of publication A3: 29.06.2006 (43) Date of publication: 29.08.2007 Bulletin 2007/35 (21) Application number: 05809234.7 (22) Date of filing: 20.11.2005

(51) International Patent Classification (IPC):  A61K 31/155(2006.01) A61K 31/661(2006.01) A61P 3/04(2006.01) A61P 25/18(2006.01) C07F 9/38(2006.01) C07F 9/6518(2006.01) A61K 31/4192(2006.01) A61K 31/675(2006.01) A61P 7/12(2006.01) A61P 25/28(2006.01) C07F 9/40(2006.01) (86) International application number: PCT/IL2005/001218 (87) International publication number: WO 2006/054298 (26.05.2006 Gazette 2006/21)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) Priority: 18.11.2004 US 628542 P (71) Applicant: Tel Aviv University Future Technology Development L.P. Tel Aviv 69 978 (IL)	(72) Inventors: ELDAR-FINKELMAN, Hagit 73142 Shoham (IL) PORTNOY, Moshe 54056 Givat Shmuel (IL) (74) Representative: Vossius & Partner  Siebertstrasse 4 81675 München 81675 München (DE)