(19)
(11) EP 1 824 480 A1

(12)

(43) Date of publication:
29.08.2007 Bulletin 2007/35

(21) Application number: 05816324.7

(22) Date of filing: 06.12.2005
(51) International Patent Classification (IPC): 
A61K 31/423(2006.01)
C07D 413/12(2006.01)
 C07D 263/58(2006.01)
A61P 25/00(2006.01)
(86) International application number:
PCT/EP2005/056506
(87) International publication number:
WO 2006/061377 (15.06.2006 Gazette 2006/24)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
Designated Extension States:
HR

(30) Priority: 08.12.2004 US 634074 P
08.12.2004 EP 04106394

(71) Applicant: Solvay Pharmaceuticals B.V.
1381 CP Weesp (NL)

(72) Inventors:
  • FEENSTRA, Roelof W., Solvay Pharmaceuticals B.V.
    NL-1381 CP Weesp (NL)
  • STOIT, Axel, Solvay Pharmaceuticals B.V.
    NL-1381 CP Weesp (NL)
  • TERPSTRA, Jan-Willem, Solvay Pharmaceuticals B.V.
    NL-1381 CP Weesp (NL)
  • PRAS-RAVES, Maria L., Solvay Pharmaceuticals B.V.
    NL-1381 CP Weesp (NL)
  • MCCREARY, Andrew C., Solvay Pharmaceuticals B.V.
    NL-1381 CP Weesp (NL)
  • VAN VLIET, Bernard J., Solvay Pharmaceuticals B.V.
    NL-1381 CP Weesp (NL)
  • HESSELINK, Mayke B., Solvay Pharmaceuticals B.V.
    NL-1381 CP Weesp (NL)
  • KRUSE, Cornelis G., Solvay Pharmaceuticals B.V.
    NL-1381 CP Weesp (NL)
  • VAN SCHARRENBURG, G., Solvay Pharmceuticals B.V.
    NL-1381 CP Weesp (NL)

(74) Representative: Verhage, Marinus et al
Octrooibureau Zoan B.V. P.O. Box 140
1380 AC Weesp
1380 AC Weesp (NL)

   


(54) PHENYLPIPERAZINE DERIVATIVES WITH A COMBINATION OF PARTIAL DOPAMINE-D2 RECEPTOR AGONISM AND SEROTONIN REUPTAKE INHIBITION