(19)

(11)

EP 1 824 846 A2

(12)

(88) Date of publication A3: 27.07.2006 (43) Date of publication: 29.08.2007 Bulletin 2007/35 (21) Application number: 05826439.1 (22) Date of filing: 30.11.2005

(51) International Patent Classification (IPC):  C07D 417/06(2006.01) A61K 31/425(2006.01) C07D 403/06(2006.01) A61P 25/28(2006.01) (86) International application number: PCT/EP2005/012765 (87) International publication number: WO 2006/058720 (08.06.2006 Gazette 2006/23)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) Priority: 02.12.2004 US 2169 24.05.2005 US 684137 P (71) Applicant: Probiodrug AG 06120 Halle/Saale (DE)	(72) Inventors: NIESTROJ, André, Johannes 06193 Sennewitz (DE) HEISER, Ulrich 06108 Halle/Saale (DE) SCHULZ, Ingo 06120 Halle/Saale (DE) RAHFELD, Jens-Ulrich 06120 Lieskau (DE) BÄR, Joachim 06108 Halle/Saale (DE) DEMUTH, Hans-Ulrich 06114 Halle/Saale (DE) (74) Representative: Hoffmann, Matthias  Probiodrug AG Weinbergweg 22 06120 Halle/Saale 06120 Halle/Saale (DE)