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EP 1 824 848 A1

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(43) Date of publication: 29.08.2007 Bulletin 2007/35 (21) Application number: 04813737.6 (22) Date of filing: 10.12.2004

(51) International Patent Classification (IPC):  C07D 453/02(2006.01) A61P 25/28(2006.01) A61K 31/439(2006.01) (86) International application number: PCT/US2004/041471 (87) International publication number: WO 2006/065233 (22.06.2006 Gazette 2006/25)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (71) Applicant: ABBOTT LABORATORIES Abbott Park, Illinois 60064-6008 (US)	(72) Inventors: JI, Jianguo Libertyville, IL 60048 (US) LI, Tao Grayslake, IL 60030 (US) MORTELL, Kathleen H. Chicago, IL (US) SCHRIMPF, Michael R. Grayslake, IL 60030 (US) NERSESIAN, Diana L. Gurnee, IL 60031 (US) PAN, Liping Gurnee, IL 60031 (US) (74) Representative: Modiano, Micaela Nadia et al Modiano Josif Pisanty & Staub Ltd Thierschstrasse 11 80538 München 80538 München (DE)