(19)

(11)

EP 1 828 122 A2

(12)

(88) Date of publication A3: 12.10.2006 (43) Date of publication: 05.09.2007 Bulletin 2007/36 (21) Application number: 05811385.3 (22) Date of filing: 08.12.2005

(51) International Patent Classification (IPC):  C07D 207/34(2006.01) C07D 211/58(2006.01) A61P 13/00(2006.01) A61P 29/00(2006.01) C07D 401/12(2006.01) A61K 31/40(2006.01) A61P 25/24(2006.01) (86) International application number: PCT/IB2005/003791 (87) International publication number: WO 2006/064351 (22.06.2006 Gazette 2006/25)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) Priority: 16.12.2004 GB 0427618 27.01.2005 US 647839 P 28.06.2005 US 695238 P (71) Applicant: Pfizer Limited Sandwich, Kent CT13 9NJ (GB)

(72) Inventors: ANDREWS, Mark David Kent CT13 9NJ (GB) BROWN, Alan Daniel Kent CT13 9NJ (GB) FISH, Paul Vincent Kent CT13 9NJ (GB) FRAY, Michael Jonathan Kent CT13 9NJ (GB) LANSDELL, Mark Ian Kent CT13 9NJ (GB) RYCKMANS, Thomas Kent CT13 9NJ (GB) STOBIE, Alan Kent CT13 9NJ (GB) WAKENHUT, Florian Kent CT13 9NJ (GB) GRAY, David L.F. Ann Arbor, MI 48105 (US) (74) Representative: Nevant, Marc et al Pfizer European Pharma Patent Department 23-25, avenue du Docteur Lannelongue 75668 Paris Cedex 14 75668 Paris Cedex 14 (FR)