REMEDIAL AGENT FOR FAT TOXICITY

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EP 1 834 639 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	07.12.2016 Bulletin 2016/49

(45)	Mention of the grant of the patent:
	27.07.2016 Bulletin 2016/30

(21)	Application number: 06702028.9

(22)	Date of filing: 04.01.2006

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International Patent Classification (IPC):

A61K 45/06^(2006.01)
A61K 31/202^(2006.01)
A61P 1/18^(2006.01)
A61P 3/06^(2006.01)
A61P 5/48^(2006.01)
A61P 9/04^(2006.01)
A61P 13/12^(2006.01)
A61P 43/00^(2006.01)

A61K 31/232^(2006.01)
A61P 1/16^(2006.01)
A61P 3/04^(2006.01)
A61P 3/10^(2006.01)
A61P 9/00^(2006.01)
A61P 13/00^(2006.01)
A61P 39/02^(2006.01)

(86)	International application number:
	PCT/JP2006/300008

(87)	International publication number:
	WO 2006/073147 (13.07.2006 Gazette 2006/28)

(54)	REMEDIAL AGENT FOR FAT TOXICITY GEGENMITTEL GEGEN DIE TOXIZITÄT VON FETTEN AGENT THÉRAPEUTIQUE CONTRE LA TOXICITÉ DES GRAISSES

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

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Priority:

04.01.2005 JP 2005000168

(43)	Date of publication of application:
	19.09.2007 Bulletin 2007/38

(73)	Proprietor: MOCHIDA PHARMACEUTICAL CO., LTD.
	Shinjuku-ku Tokyo 160-8515 (JP)

(72)	Inventors:
	SHIMANO, Hitoshi Tsukuba-shi, Ibaraki, 305-0032 (JP) KATO, Toyonori Shinjuku-ku, Tokyo, 160-8515 (JP)

(74)	Representative: Grünecker Patent- und Rechtsanwälte PartG mbB
	Leopoldstraße 4 80802 München 80802 München (DE)

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References cited: :

WO-A-2004/078166

GHOSH S ET AL: "Role of dietary fatty acids and acute hyperglycemia in modulating cardiac cell death" NUTRITION, ELSEVIER INC, US, vol. 20, no. 10, 1 October 2004 (2004-10-01), pages 916-923, XP004594916 ISSN: 0899-9007
ITOH Y. ET AL.: 'Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40' NATURE vol. 422, no. 6928, 2003, pages 173 - 176, XP002903889
WOODMAN R. J. ET AL.: 'Effects of purified eicosapentaenoic and docosahexaenoic acids on glycemic control, blood pressure, and serum lipids in type 2 diabetic patients with treated hypertension' AMERICAN JOURNAL OF CLINICAL NUTRITION vol. 76, no. 5, 2002, pages 1007 - 1015, XP002999559
OPARA E. C. ET AL.: 'Characterization of the Isulinotropic Potency of Polyunsaturated Fatty Acids' ENDOCRINOLOGY vol. 130, no. 2, 1992, pages 657 - 662, XP002999561
ETO K. ET AL.: 'Genetic Manipulations of Fatty Acid Metabolism in beta-Cells Are Associated With Dysregulated Insulin Secretion' DIABETES vol. 51, no. 3, 2002, pages 414 - 420, XP002999562
'Lipid disorder and lipotoxicity in diabetes mellitus' THE CELL vol. 33, no. 8, 2001, pages 302 - 305, XP002999563
'free fatty acid, lipotoxicity, obesity' 5. 2003, pages 24 - 29, XP002999564


	Remarks:
	The file contains technical information submitted after the application was filed and not included in this specification

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).