(19)

(11)

EP 1 838 291 A2

(12)

(88) Date of publication A3: 01.03.2007 (43) Date of publication: 03.10.2007 Bulletin 2007/40 (21) Application number: 06718892.0 (22) Date of filing: 20.01.2006

(51) International Patent Classification (IPC):  A61K 9/36(2006.01) A61K 31/195(2006.01) A61K 9/22(2006.01) (86) International application number: PCT/US2006/001887 (87) International publication number: WO 2006/078811 (27.07.2006 Gazette 2006/30)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK YU (30) Priority: 21.01.2005 US 645857 P (71) Applicants: Pharmanova Inc. West Henrietta, NY 14586 (US) Quay Pharmaceuticals Ltd. 3-4 Apex Court, Bassendal Road Bromborough, Wirral CH62 3RE (GB)	(72) Inventors: BROWN, Rodney, A. Victor, New York 14564 (US) CURRY, Stephen, H. Victor, New York 14564 (US) RUBENSTEIN, Michael Liverpool L18 2EJ (GB) VIOLANTE, Michael, R. Pittsford, New York 14534 (US) (74) Representative: Daniels, Jeffrey Nicholas et al Page White & Farrer Bedford House John Street London, WC1N 2BF London, WC1N 2BF (GB)