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(11)

EP 1 841 882 A1

(12)

(43) Date of publication: 10.10.2007 Bulletin 2007/41 (21) Application number: 04815061.9 (22) Date of filing: 21.12.2004

(51) International Patent Classification (IPC):  C12Q 1/48(2006.01) C07K 16/00(2006.01) G01N 33/68(2006.01) C07K 7/00(2006.01) (86) International application number: PCT/US2004/042940 (87) International publication number: WO 2006/068640 (29.06.2006 Gazette 2006/26)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (71) Applicant: Cell Signaling Technology, Inc. Danvers MA 01923 (US)

(72) Inventors: MORITZ, Albrecht Burlington, MA 01803 (US) LI, Yu Boston, MA 02114 (US) FARNSWORTH, Charles Reading, MA 01867 (US) RIKOVA, Klarisa Concord, MA 01742 (US) LEE, Kimberly Andover, MA 01810 (US) GUO, Ailan Salem, MA 01970 (US) POLAKIEWICZ, Roberto Lexington, MA 02421 (US) (74) Representative: Hill, Justin John  McDermott Will & Emery UK LLP 7 Bishopsgate London EC2N 3AR London EC2N 3AR (GB)