(19)

(11)

EP 1 843 779 A2

(12)

(88) Date of publication A3: 05.10.2006 (43) Date of publication: 17.10.2007 Bulletin 2007/42 (21) Application number: 06720021.2 (22) Date of filing: 01.02.2006

(51) International Patent Classification (IPC):  A61K 38/04(2006.01) (86) International application number: PCT/US2006/003461 (87) International publication number: WO 2006/083906 (10.08.2006 Gazette 2006/32)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK YU (30) Priority: 01.02.2005 US 648391 P (71) Applicant: Attenuon, LLC San Diego, CA 92121 (US)	(72) Inventors: MAZAR, Andrew, P San Diego, CA 92101 (US) HEIATI, Hashem San Diego, CA 92130 (US) SCHRIER, Jay La Jolla, CA 92037 (US) LI, Ming New York, NY 10010 (US) HARRIS, Scott San Diego, CA 92109 (US) (74) Representative: Jones Day  Rechtsanwälte, Attorneys-at-Law, Patentanwälte Prinzregentenstrasse 11 80538 München 80538 München (DE)