RNA INTERFERENCE MEDIATED INHIBITION OF RETINOBLASTOMA (RBI) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) - Patent 1844147

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EP 1 844 147 A2

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(88)	Date of publication A3:
	25.01.2007

(43)	Date of publication:
	17.10.2007 Bulletin 2007/42

(21)	Application number: 06718871.4

(22)	Date of filing: 18.01.2006

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International Patent Classification (IPC):

C12N 15/11^(2006.01)

(86)	International application number:
	PCT/US2006/001863

(87)	International publication number:
	WO 2006/078798 (27.07.2006 Gazette 2006/30)

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

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Priority:

18.01.2005 US 39680
15.02.2005 US 58582
06.05.2005 US 678531 P
29.07.2005 US 703946 P
15.11.2005 US 737024 P

(71)	Applicant: SIRNA THERAPEUTICS, INC.
	Boulder, CO 80301 (US)

(72)	Inventors:
	CHRISTIANO, Angela New York, New York 10032 (US) McSWIGGEN, James Boulder, Colorado 80301 (US)

(74)	Representative: Hussain, Deeba
	Merck & Co., Inc. Hertford Road Hoddesdon Hertfordshire EN11 9BU Hoddesdon Hertfordshire EN11 9BU (GB)

(54)	RNA INTERFERENCE MEDIATED INHIBITION OF RETINOBLASTOMA (RBI) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)